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Vitamin B12

Hydroxycobalamin (ohcbl, or B12a) is a natural form of vitamin B12, or one of the vitamin B12 classes. It is a basic member of the cobalamine group. Many of the bacteria that produce vitamins commercially produce vitamin B12 in the form of hydroxycobalamin. Hydroxycobalamin is dark red. Vitamin B12 in the human body is not normally present in the form of hydroxycobalamin. However, in humans, hydroxycobalamin is easily converted into a useful coenzyme form of vitamin B12. The medicinal hydroxycobalamin product is its sterile injection, which is used to treat vitamin deficiency and cyanide poisoning (because it is compatible with cyanide ions). Hydroxycobalamin has also been used as a  scavenger..


Function

At present, there are four kinds of vitamin B12 in the world API market. They are hydroxycobalamin, Mecobalamin, cyanobalamin and cobalamin adenosine. This is because the central ion in B12 molecule has different functional groups, so it is called different names. Hydroxycobalamin is called hydroxycobalamin because the central ion of B12 is connected with hydroxyl group. Among the four B12 molecules, hydroxycobalamin has the best water solubility and slow metabolism in urine, which is also known as long-acting cobalamin. Although the absorption rate is not comparable to that of cyanocobalan and Mecobalamin, its concentration in the eye is very high, which can greatly relieve visual fatigue and nourish the optic nerve. Therefore, it has a certain curative effect on amblyopia caused by poisoning. In addition, hydroxycobalamin can quickly combine with free cyanide to form nontoxic cyanobalamin in aqueous solution, so its other therapeutic effect is the antidote of cyanide poisoning


Product specification

Items

Standards

Results

Physical and chemical analysis

Appearance

Pale red to brown powder
hygroscopicity

Complies

Identification

Have maximum absorption at 361±1nm,550±2nm

Complies

Loss on drying

≤12%

9.0%

Assay

09.0%-1.3%

1%

Residue on ignition

≤0.1%

0.06%

Heavy Metal

Arsenic(As)

≤0.1mg/kg

Complies

Lead(Pb)

≤1mg/kg

Complies

Microbiological Tests

Total Plate Count

≤1000cfu/g

Complies

Mould & yeast

≤100cfu/g

Complies

Coliform

Negative

Negative

E.coli

Negative

Negative

Salmonella

Negative

Negative

Staphylococcus

Negative

Negative

General Information

Package: 25kg/ carton

Storage: The product should be stored in a dry and cool place, and prevent moisture,sunlight, pest-outbreak,pollution of harmful substance and other damage.

Shelf life

3 years